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1

Maternal folic acid supplementation with vitamin B 12 deficiency during pregnancy and lactation affects the metabolic health of adult female offspring but is dependent on offspring diet

Henderson, Amanda M., Tai, Daven C., Aleliunas, Rika E., Aljaadi, Abeer M., Glier, Melissa B., Xu, Eric E., Miller, Joshua W., Verchere, C. Bruce, Green, Tim J., Devlin, Angela M.

Journal:

The FASEB Journal

Year:

2018

Language:

english

File:

PDF, 1.91 MB

english, 2018

2

Cholesterol in β-cell Dysfunction: The Emerging Connection Between HDL Cholesterol and Type 2 Diabetes

Liam R. Brunham, Janine K. Kruit, Michael R. Hayden, C. Bruce Verchere

Journal:

Current Diabetes Reports

Year:

2010

Language:

english

File:

PDF, 231 KB

english, 2010

3

The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice

J. Vidal,C. Bruce Verchere,S. Andrikopoulos,F. Wang,R. Hull,M. Cnop…

Journal:

Year:

2003

Language:

english

File:

PDF, 372 KB

english, 2003

4

Islet amyloid polypeptide and type 2 diabetes

Lucy Marzban, Kirily Park, C Bruce Verchere

Journal:

Experimental Gerontology

Year:

2003

Language:

english

File:

PDF, 104 KB

english, 2003

5

Effect of galanin on endocrine secretions from the isolated perfused rat stomach and pancreas

Yin Nam Kwok, C. Bruce Verchere, Christopher H.S. McIntosh, John C. Brown

Journal:

European Journal of Pharmacology

Year:

1988

Language:

english

File:

PDF, 414 KB

english, 1988

6

Amyloid inhibitors enhance survival of cultured human islets

Kathryn J. Potter, Louise A. Scrocchi, Garth L. Warnock, Ziliang Ao, Marika A. Younker, Lawrence Rosenberg, Mark Lipsett, C. Bruce Verchere, Paul E. Fraser

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2009

Language:

english

File:

PDF, 767 KB

english, 2009

7

Synergistic inhibition of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human pancreatic β cells by Bcl-2 and X-linked inhibitor of apoptosis

Dawei Ou, Xiaojie Wang, Daniel L. Metzger, Roger F.L. James, Paolo Pozzilli, Annette Plesner, Robert G. Korneluk, C. Bruce Verchere, Aubrey J. Tingle

Journal:

Human Immunology

Year:

2005

Language:

english

File:

PDF, 377 KB

english, 2005

8

The Sulfated Triphenyl Methane Derivative Acid Fuchsin Is a Potent Inhibitor of Amyloid Formation by Human Islet Amyloid Polypeptide and Protects against the Toxic Effects of Amyloid Formation

Fanling Meng, Andisheh Abedini, Annette Plesner, Chris T. Middleton, Kathryn J. Potter, Martin T. Zanni, C. Bruce Verchere, Daniel P. Raleigh

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.57 MB

english, 2010

9

Proteoglycans synthesized and secreted by pancreatic islet β-cells bind amylin

Susan Potter-Perigo, Rebecca L. Hull, Christina Tsoi, Kathleen R. Braun, Sofianos Andrikopoulos, Jeanette Teague, C. Bruce Verchere, Steven E. Kahn, Thomas N. Wight

Journal:

Archives of Biochemistry and Biophysics

Year:

2003

Language:

english

File:

PDF, 415 KB

english, 2003

10

Evidence that galanin is a parasympathetic, rather than a sympathetic, neurotransmitter in the baboon pancreas

C.Bruce Verchere, Stephan Kowalyk, Donna J. Koerker, Denis G. Baskin, Gerald J. Taborsky Jr.

Journal:

Regulatory Peptides

Year:

1996

Language:

english

File:

PDF, 829 KB

english, 1996

11

Evidence that vasoactive intestinal polypeptide is a parasympathetic neurotransmitter in the endocrine pancreas in dogs

Peter J Havel, Beth E Dunning, C.Bruce Verchere, Denis G Baskin, Thomas O'Dorisio, Gerald J Taborsky Jr

Journal:

Regulatory Peptides

Year:

1997

Language:

english

File:

PDF, 350 KB

english, 1997

12

Metabolic stress, IAPP and islet amyloid

J. Montane, A. Klimek-Abercrombie, K. J. Potter, C. Westwell-Roper, C. Bruce Verchere

Journal:

Diabetes, Obesity and Metabolism

Year:

2012

Language:

english

File:

PDF, 683 KB

english, 2012

13

Stimulus-specific inhibition of insulin release from rat pancreas by both rat and porcine galanin

C. Bruce Verchere, Yin Nam Kwok, John C. Brown

Journal:

Year:

1992

Language:

english

File:

PDF, 503 KB

english, 1992

14

Canine galanin: sequence, expression and pancreatic effects

Michael R. Boyle, C. Bruce Verchere, Gary McKnight, Shannon Mathews, Kathy Walker, Gerald J. Taborsky Jr.

Journal:

Regulatory Peptides

Year:

1994

Language:

english

File:

PDF, 1.89 MB

english, 1994

15

The Flavanol (−)-Epigallocatechin 3-Gallate Inhibits Amyloid Formation by Islet Amyloid Polypeptide, Disaggregates Amyloid Fibrils, and Protects Cultured Cells against IAPP-Induced Toxicity

Meng, Fanling, Abedini, Andisheh, Plesner, Annette, Verchere, C. Bruce, Raleigh, Daniel P.

Journal:

Year:

2010

Language:

english

File:

PDF, 4.93 MB

english, 2010

16

Public Health

Westwell-Roper, Clara, Ehses, Jan A., Verchere, C. Bruce

Journal:

Year:

1940

Language:

english

File:

PDF, 450 KB

english, 1940

17

Activation of Toll-like Receptor 2 by Islet Amyloid Polypeptide: A Trigger for Islet Inflammation in Type 2 Diabetes?

Westwell-Roper, Clara, Ehses, Jan A., Verchere, C. Bruce

Journal:

Canadian Journal of Diabetes

Year:

2012

Language:

english

File:

PDF, 148 KB

english, 2012

18

Autologous Islet Transplant Recipients have Defective (β-cell Proinsulin Processing

Klimek, Agnieszka M., Soukhatcheva, Galina, Thompson, David M., Warnock, Garth L., Salehi, Marzieh, Rilo, Horacio, D'alessio, David, Panagiotopoulos, Constadina, verchere, C. Bruce

Journal:

Canadian Journal of Diabetes

Year:

2008

Language:

english

File:

PDF, 753 KB

english, 2008

19

Aboriginal youth with insulin resistance have elevated levels of circulating proinsulin but decreased proinsulin:insulin ratios

Klimek, Agnieszka M., Verchere, C. Bruce, Panagiotopoulos, Constadina

Journal:

Canadian Journal of Diabetes

Year:

2008

Language:

english

File:

PDF, 608 KB

english, 2008

20

Cell-specific Expression of the Anti-apoptotic Gene XIAP Protects Islet Allografts and Induces Donor-Specific Tolerance

Obach, Merce, Montane, Joel, Soukhatcheva, Galina, Orban, Paul, Verchere, C. Bruce

Journal:

Canadian Journal of Diabetes

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

21

Chemokine Induced Tolerance in Mouse Islet Allografts

Montane, Joel, Obach, Merce, Bischoff, Loraine, Soukhatcheva, Galina, Orban, Paul C., Hardenberg, Gijs, Levings, Megan K., Tan, Rusung, Verchere, C. Bruce

Journal:

Canadian Journal of Diabetes

Year:

2012

Language:

english

File:

PDF, 31 KB

english, 2012

22

Role of the Toll-like Receptor Signalling Molecule MyD88 in β-cell Function.

Hamilton, Meredith J., Soukhatcheva, Galina, Verchere, C. Bruce

Journal:

Canadian Journal of Diabetes

Year:

2008

Language:

english

File:

PDF, 704 KB

english, 2008

23

The Canadian Diabetes Association Invests More Than $6.8 million in Research

VandenBerg, Polly, Verchere, C. Bruce

Journal:

Canadian Journal of Diabetes

Year:

2009

Language:

english

File:

PDF, 462 KB

english, 2009

24

Local Expression of B7-H4 by Transducing Recombinant Adenovirus in Islet Grafts Improves Allotransplant Outcomes.

Wang, Xiaojie, Hao, Jianqiang, Metzger, Daniell, Mui, Alice, Ao, Ziliang, Bruce Verchere, C., Chen, Lieping, Ou, Dawei, Warnock, Garthl

Journal:

Canadian Journal of Diabetes

Year:

2008

Language:

english

File:

PDF, 231 KB

english, 2008

25

2009 Clinician-Scientist Award Recipient, Dr. Andrew Advani

VandenBerg, Polly, Bruce Verchere, C.

Journal:

Canadian Journal of Diabetes

Year:

2010

Language:

english

File:

PDF, 448 KB

english, 2010

26

2008 Clinician-Scientist Awardee, Dr. Dina Panagiotopoulos

Vandenberg, Polly, Verchere, Bruce

Journal:

Canadian Journal of Diabetes

Year:

2009

Language:

english

File:

PDF, 427 KB

english, 2009

27

2009 Canadian Diabetes Association, Great-West Life, London Life Canada Life Young Scientist Award Winner: Dr. Vincent Poitout

VandenBerg, Polly, Bruce Verchere, C.

Journal:

Canadian Journal of Diabetes

Year:

2009

Language:

english

File:

PDF, 428 KB

english, 2009

28

Islet Amyloid Formation Associated with Hyperglycemia in Transgenic Mice with Pancreatic Beta Cell Expression of Human Islet Amyloid Polypeptide

C. Bruce Verchere, David A. D'Alessio, Richard D. Palmiter, Gordon C. Weir, Susan Bonner-Weir, Denis G. Baskin and Steven E. Kahn

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.33 MB

english, 1996

29

Role of Carboxypeptidase E in Processing of Pro-Islet Amyloid Polypeptide in β-Cells

Marzban, Lucy, Soukhatcheva, Galina, Verchere, C. Bruce

Journal:

Year:

2005

Language:

english

File:

PDF, 478 KB

english, 2005

30

Rifampicin Does Not Prevent Amyloid Fibril Formation by Human Islet Amyloid Polypeptide but Does Inhibit Fibril Thioflavin-T Interactions: Implications for Mechanistic Studies of β-Cell Death †

Meng, Fanling, Marek, Peter, Potter, Kathryn J., Verchere, C. Bruce, Raleigh, Daniel P.

Journal:

Year:

2008

Language:

english

File:

PDF, 12.75 MB

english, 2008

31

Characterization of Acetylcholine-induced Increases in Cytosolic Free Calcium Concentration in Individual Rat Pancreatic β-cells

Wang, Jian, Verchere, C. Bruce, McIntosh, Christopher H.S., Brown, John C.

Journal:

Cell Communication and Adhesion

Year:

1994

Language:

english

File:

PDF, 808 KB

english, 1994

32

Glucose-dependent insulinotropic polypeptide stimulated insulin release from a tumor-derived β-cell line (βTC3)

Kieffer, Tim J., Verchere, C. Bruce, Fell, Charlene D., Huang, Zhongxian, Brown, John C., Pederson, Raymond A.

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1993

Language:

english

File:

PDF, 859 KB

english, 1993

33

IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice

Westwell-Roper, Clara Y., Chehroudi, Cyrus A., Denroche, Heather C., Courtade, Jaques A., Ehses, Jan A., Verchere, C. Bruce

Journal:

Year:

2015

Language:

english

File:

PDF, 1.67 MB

english, 2015

34

Loss of Cyp8b1 Improves Glucose Homeostasis by Increasing GLP-1

Kaur, Achint, Patankar, Jay V., de Haan, Willeke, Ruddle, Piers, Wijesekara, Nadeeja, Groen, Albert K., Verchere, C. Bruce, Singaraja, Roshni R., Hayden, Michael R.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

35

Blockade of both B7-H4 and CTLA-4 co-signaling pathways enhances mouse islet allograft survival

Wang, Xiaojie, Hao, Jianqiang, Metzger, Daniel L., Mui, Alice, Lee, I-Fang, Akhoundsadegh, Noushin, Chen, C. Lieping, Ou, Dawei, Ao, Ziliang, Verchere, C. Bruce, Warnock, Garth L.

Journal:

Year:

2012

Language:

english

File:

PDF, 7.75 MB

english, 2012

36

XIAP inhibition of β-cell apoptosis reduces the number of islets required to restore euglycemia in a syngeneic islet transplantation model

Plesner, Annette, Soukhatcheva, Galina, Korneluk, Robert G., Verchere, C. Bruce

Journal:

Year:

2010

Language:

english

File:

PDF, 875 KB

english, 2010

37

Translational Control of Glucose-Induced Islet Amyloid Polypeptide Production in Pancreatic Islets

Alarcon, Cristina, Verchere, C. Bruce, Rhodes, Christopher J.

Journal:

Year:

2012

Language:

english

File:

PDF, 513 KB

english, 2012

38

Role of the TLR signaling molecule TRIF in β-cell function and glucose homeostasis

Hutton, Meredith J. H., Soukhatcheva, Galina, Johnson, James D., Verchere, C. Bruce

Journal:

Year:

2010

Language:

english

File:

PDF, 1.07 MB

english, 2010

39

Regulation of Glycosylphosphatidylinositol-Specific Phospholipase D Secretion from βTC3 cells 1

Deeg, Mark A., Verchere, C. Bruce

Journal:

Year:

1997

Language:

english

File:

PDF, 524 KB

english, 1997

40

Processing of Pro-Islet Amyloid Polypeptide in the Constitutive and Regulated Secretory Pathways of β Cells

Marzban, Lucy, Trigo-Gonzalez, Genny, Verchere, C. Bruce

Journal:

Molecular Endocrinology

Year:

2005

Language:

english

File:

PDF, 287 KB

english, 2005

41

Kinetics and genomic profiling of adult human and mouse β-cell maturation

Szabat, Marta, Pourghaderi, Poya, Soukhatcheva, Galina, Verchere, C. Bruce, Warnock, Garth L., Piret, James M., Johnson, James D

Journal:

Year:

2011

Language:

english

File:

PDF, 3.87 MB

english, 2011

42

Differential activation of innate immune pathways by distinct islet amyloid polypeptide (IAPP) aggregates

Westwell-Roper, Clara, Denroche, Heather C., Ehses, Jan A., Verchere, C. Bruce

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.07 MB

english, 2016

43

ABCA1 deficiency and cellular cholesterol accumulation increases islet amyloidogenesis in mice

Wijesekara, Nadeeja, Kaur, Achint, Westwell-Roper, Clara, Nackiewicz, Dominika, Soukhatcheva, Galina, Hayden, Michael R., Verchere, C. Bruce

Journal:

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

44

Glucagon-Like Peptide-1 Receptor Agonists: Beta-Cell Protection or Exhaustion?

van Raalte, Daniël H, Verchere, C. Bruce

Journal:

Trends in Endocrinology & Metabolism

Year:

2016

Language:

english

File:

PDF, 353 KB

english, 2016

45

Islet Allograft Rejection Is Independent of Toll-Like Receptor Signaling in Mice

Hutton, Meredith J.H., Westwell-Roper, Clara, Soukhatcheva, Galina, Plesner, Annette, Dutz, Jan P., Verchere, C Bruce

Journal:

Transplantation Journal

Year:

2009

Language:

english

File:

PDF, 1.28 MB

english, 2009

46

Different Effects of FK506, Rapamycin, and Mycophenolate Mofetil on Glucose-Stimulated Insulin Release and Apoptosis in Human Islets

Johnson, James D., Ao, Ziliang, Ao, Peter, Li, Hong, Dai, Long-Jun, He, Zehua, Tee, May, Potter, Kathryn J., Klimek, Agnieszka M., Meloche, R. Mark, Thompson, David M., Verchere, C. Bruce, Warnock, Ga

Journal:

Cell Transplantation

Year:

2009

Language:

english

File:

PDF, 4.46 MB

english, 2009

47

Extraterritorial Effects of United States Tax Laws

Robert T. Cole, Richard C. Pugh, David S. Foster, Joseph H. Guttentag, Mark R. Joelson, William J. Caveney and Bruce Verchere

Journal:

The International Lawyer

Year:

1978

Language:

english

File:

PDF, 4.53 MB

english, 1978

48

HDL and LDL cholesterol significantly influence β-cell function in type 2 diabetes mellitus

Kruit, Janine K, Brunham, Liam R, Verchere, C Bruce, Hayden, Michael R

Journal:

Current Opinion in Lipidology

Year:

2010

Language:

english

File:

PDF, 294 KB

english, 2010

49

Erratum. Small Interfering RNA—Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Diabetes 2008;57:3045—3055

Marzban, Lucy, Tomas, Alejandra, Becker, Thomas C., Rosenberg, Lawrence, Oberholzer, Jose, Fraser, Paul E., Halban, Philippe A., Verchere, C. Bruce

Journal:

Year:

2016

Language:

english

File:

PDF, 916 KB

english, 2016

50

Endogenous Expression of B7-H4 Improves Long-term Murine Islet Allograft Survival

Wang, Xiaojie, Hao, Jianqiang, Metzger, Daniel L., Mui, Alice, Lee, I-Fang, Akhoundsadegh, Noushin, Ao, Ziliang, Chen, Lieping, Ou, Dawei, Verchere, C. Bruce, Warnock, Garth L.

Journal:

Transplantation Journal

Year:

2013

Language:

english

File:

PDF, 824 KB

english, 2013